Existence-threatening respiratory difficulties (respiratory melancholy). Promethazine Hydrochloride and Codeine Phosphate Oral Resolution could cause respiration issues (respiratory despair) that may come about Anytime through treatment method and can cause Dying. Your possibility of respiratory problems is best if you very first get started taking Promethazine Hydrochloride and Codeine Phosphate Oral Alternative, are taking other medicines that may cause respiration troubles, have particular lung troubles, are aged or have certain other health issues.
This medication may possibly include sugar and/or Alcoholic beverages. Caution is encouraged if you have diabetic issues, Liquor dependence, or liver condition. Check with your doctor or pharmacist about employing this solution properly.
Probably the most notable of those unfortunate overdoses could be the late rapper and singer Juice WRLD, who died of the codeine overdose in 2021, just times just after his twenty first birthday.
Watch individuals with a history of seizure Diseases for worsened seizure Management all through promethazine HCl and codeine phosphate oral Alternative therapy.
Infertility Persistent usage of opioids, for instance codeine, a ingredient of promethazine HCl and codeine phosphate oral Answer, could trigger diminished fertility in ladies and males of reproductive opportunity.
Hazard of Medication Glitches: Guarantee precision when prescribing, dispensing, and administering the oral solution; dosing faults as a consequence of confusion in between mg and mL, and various codeine solutions of various concentrations can lead to accidental overdose and Demise.
The presence of Alcoholic beverages or other medication in lean can improve the likelihood of respiratory depression, raising the chances of overdose or Loss of life.
Even though there aren't any conventional opioid tapering schedules suited to all sufferers, excellent clinical observe dictates tapering in compact increments (e.
Emotion or being Unwell (nausea or vomiting) Consider codeine with or simply just following a meal or snack to simplicity feelings of sickness.
FDA Drug Security Interaction: FDA involves labeling alterations for prescription opioid cough and website cold medicines to Restrict their use to adults 18 decades and more mature
For instance, someone that snorts typical cocaine could possibly deal with 3 strains. After they make an effort to do the same with pure cocaine, it might cause overdose that leads to cardiac arrest and Loss of life.
Promethazine is greatly distributed in physique tissues. Promethazine has superior protein binding with about 80 to 93% of promethazine bound to plasma proteins. Promethazine passes the blood brain barrier and the placental barrier.
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Acute or extreme bronchial bronchial asthma in an unmonitored location or in absence of resuscitative tools. (four)